Paolo Marzano obtained his Master’s degree in Medical Biotechnology and Molecular Medicine from the University of Milan in 2022, with a strong focus on experimental immunology. He is currently finishing his PhD in Experimental Medicine and works as a bioinformatician at the Unit of Clinical and Experimental Immunology at IRCCS Humanitas Research Hospital, under the supervision of Professor Domenico Mavilio.
His scientific background integrates immunology with computational biology, and his work focuses on the application of multi-omics approaches to unravel the complexity of the immune system in cancer and immune-mediated diseases.
Since the beginning of his doctoral training, Paolo has been actively involved in research projects aimed at dissecting immune-tumor interactions through the integrative analysis of single-cell technologies, including single-cell RNA sequencing, scTCR sequencing (both conventional αβ and unconventional γδ), CITE-seq, and high-dimensional spectral flow cytometry, to achieve a high-resolution characterization of the immune landscape across different clinical contexts. His research focuses on multiple pathological conditions, including colorectal cancer and colorectal liver metastases, thymic epithelial tumors, gynecological malignancies (endometrial and ovarian cancers), and myelodysplastic syndromes (MDS).