Edoardo D’Imprima is the coordinator of the Correlative Light-Electron Microscopy (CLEM) Core facility at Humanitas Research Hospital in Milan. He studied pharmaceutical biotechnologies at the University of Eastern Piedmont in Novara.
He obtained his M.Sc. in Pharmaceutical Biotechnology at the University of Easter Piedmont in Novara. From 2010 to 2012 he worked as a staff scientist at the in-vitro quality control and viral safety unit for Merck Serono Italia (Ivrea, IT). From 2013 to 2018 he completed his PhD in chemistry at the Max Planck Institute of Biophysics (Frankfurt am Main, DE) focusing on the structural characterization of protein complexes using single-particle cryoEM.
From 2019 to 2023 he worked as a postdoc at the European Molecular Biology Laboratory EMBL (Heidelberg, DE) investigating cancer onset in tissues using organoid models. For that, together with industrial partners, he developed a multimodal imaging pipeline to link live cell imaging, to ultrastructural resolution by correlative light-electron microscopy (CLEM) and cryo-FIB/SEM volume imaging, to molecular resolution by lift-out and cryo-electron tomography (cryoET).
He specializes in image processing and the structural biology of macromolecular complexes, either isolated or directly in-cell, using SEM and TEM at room temperature and cryogenic regimes. He aims to leverage the combined power of electron and light microscopy to understand how to cure diseases. He believes Humanitas Reaserch Hospital can improve patients’ lives by providing cutting-edge imaging tools, traditionally employed in basic research, to clinicians.