The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33.
Liguori M
Cell Mol Immunol. 2020 Jul 29;18(3):711-722. doi: 10.1038/s41423-020-0501-0
Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity.
Anfray C
J Immunother Cancer. 9(9)doi: 10.1136/jitc-2021-002408
Mannose-modified hyaluronic acid nanocapsules for the targeting of tumor-associated macrophages.
Fernández-Mariño I
Drug Deliv Transl Res. 2022 Dec 6;13(7):1896-1911. doi: 10.1007/s13346-022-01265-9
Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer.
Kamal MA
Cancers (Basel). 2022 May 27;14(11)doi: 10.3390/cancers14112653
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting.
Erreni M
Theranostics. 2023 Jan 1;13(1):355-373. doi: 10.7150/thno.77560
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy.
Aiuti A
J Clin Invest. 117(8):2233-40.
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients.
Cassani B
Blood. 2008 Jan 24;111(8):4209-19. doi: 10.1182/blood-2007-05-092429
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations.
Guerrini MM
Am J Hum Genet. 83(1):64-76. doi: 10.1016/j.ajhg.2008.06.015
Gene therapy for immunodeficiency due to adenosine deaminase deficiency.
Aiuti A
N Engl J Med. 360(5):447-58. doi: 10.1056/NEJMoa0805817
Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.
Cassani B
Blood. 2009 Aug 3;114(17):3546-56. doi: 10.1182/blood-2009-02-202085