Facility

Multiscale Immunoimaging

Multiscale Immunoimaging

Andrea Doni

Head of Unit

The Multiscale Immunoimaging Unit provides access to state-of-art light microscopy for scientists within and outside the institute, and performs independent and collaborative research for the development of advanced imaging-based technology.

The Unit of Multiscale Immunoimaging comprises a wide range of microscopes for live or fixed samples, including in vivo optical imaging instruments for luminescence and fluorescence tomography. High-capacity network of digital workstations is also available for the processing and analysis of imaging data.

The staff is involved in a wide range of scientific collaborations to support users in their studies in different fields of research, such as Oncology, Immunology, Neuroscience and Cardiology. The staff is also focused to the development of new methodologies and techniques aimed at significantly enhance bioimaging research.

major objectives of the Unit

Set up, maintain and develop optical technology for basic and advanced research

Provide theoretical and practical training to introduce researchers to optical and advanced imaging applications

Perform independent and collaborative research for the development of advanced imaging-based technology.

among our technologies

Bright-field microscopes

Wide-field fluorescence microscopes

Confocal microscopes

Super-Resolution (STED) mode

Single-Molecule Detection (SMD, FLIM/FCS) mode

Multi-photon microscope

Luminescence tomography

Fluorescence tomography

Metal-tagged Imaging Mass Cytometry

Machinery

We use high end technology of the latest industry standarts

Confocal Microscope FV1000
Confocal Microscope FV1000
LEICA SP8 Confocal Microscope (Basic)
LEICA SP8 Confocal Microscope (Basic)
LEICA SP8 Confocal Microscope (Advanced)
LEICA SP8 Confocal Microscope (Advanced)
LEICA SP5 Confocal Microscope
LEICA SP5 Confocal Microscope
LEICA SP8 STED3X SMD/FCS Confocal Microscope
LEICA SP8 STED3X SMD/FCS Confocal Microscope
Widefield CellR live cell imaging
Widefield CellR live cell imaging
LEICA DMi8 Wide-Field Microscope (Live Cell imaging)
LEICA DMi8 Wide-Field Microscope (Live Cell imaging)
IVIS Lumina III
IVIS Lumina III
FMT2000 (Fluorescence Tomography system)
FMT2000 (Fluorescence Tomography system)
Tissue optical clearing system
Tissue optical clearing system
Multiphoton Lavision Trimscope FLIM
Multiphoton Lavision Trimscope FLIM
Slide Scanner vs120 dotSlide
Slide Scanner vs120 dotSlide
Hyperion™ Imaging System
Hyperion™ Imaging System

Selected publications

Multiscale Immunoimaging Publications

Serum Amyloid P component is an essential element of resistance against Aspergillus fumigatus. Doni A, Parente R, Laface I, Magrini...

Facility Staff

Multiscale Immunoimaging
Damiano Zanini

Technologist

Multiscale Immunoimaging
Maria Rita Fumagalli

Data Scientist

Multiscale Immunoimaging
Raffaella Parente

Technologist

Multiscale Immunoimaging
Marco Erreni

Technologist

Multiscale Immunoimaging
Andrea Doni

Head of Unit